From Business: Drury Inn & Suites is conveniently located off I-55 in Sikeston near local legend Lambert’s Café. Sikeston is halfway between St. Louis and Memphis in the Missouri Bootheel,…

From Business: Settle in for a relaxing stay at the Sikeston’s newest hotel. Our Hampton Inn Sikeston hotel is located off Highway 60 and Interstate 55, just minutes from historic downtown…

"It was my first time staying at a Best Western and I enjoyed it. I was suprised to see how much space we had in our room. But, it was a good amount of space for the cost of the…"

From Business: IHG Rewards Club Members: Get better savings with YOUR RATE. Book hotels direct at holidayinnexpress.com for our lowest rates. You won't find these anywhere else. Large…

From Business: See why so many travelers make Comfort Inn & Suites Sikeston their hotel of choice when visiting Sikeston. Providing an ideal mix of value, comfort and convenience, it offers a…

From Business: This wyndham Hotels affiliate is a all Suite property with large bedrooms and living rooms, 2 LED television in each room, located near restaurants, Sikeston Jaycee Bootheel…

From Business: Enjoy a comfortable stay at the newest hotel in Sikeston, MO. We are conveniently located off Highway 60 and Interstate 55, very close to historic downtown and a short walk to…

From Business: Our brand-new hotel in Sikeston, MO is conveniently located off Highway 60 and Interstate 55, very close to historic downtown and a short walk to a variety of shops and…