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      Motels in East Prairie, MO

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      4. Pear Tree Inn Sikeston

      Pear Tree Inn Sikeston
      573-471-4100Call NowVisit Website
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      MotelsLodgingBed & Breakfast & Inns

      2602 E Malone Ave, Sikeston, MO 63801

      OPEN 24 HOURS

      From Business: The Pear Tree Inn Sikeston is conveniently located off I-55 in Sikeston near shopping and dining at local legend Lambert’s Café. Sikeston is halfway between St. Louis and…

      5. Holiday Inn Express & Suites Sikeston

      Holiday Inn Express & Suites Sikeston
      800-345-8082Call NowVisit Website
      Directions
      MotelsHotelsLodging

      115 Hospitality Dr, Sikeston, MO 63801

      From Business: IHG Rewards Club Members: Get better savings with YOUR RATE. Book hotels direct at holidayinnexpress.com for our lowest rates. You won't find these anywhere else. Large…

      YP
      34 Years
      in Business

      6. Days Inn & Suites by Wyndham Sikeston

      Days Inn & Suites by Wyndham Sikeston
      573-564-4066Call NowVisit Website
      Directions
      MotelsLodgingHotels

      220 S Interstate Dr, Sikeston, MO 63801

      From Business: This wyndham Hotels affiliate is a all Suite property with large bedrooms and living rooms, 2 LED television in each room, located near restaurants, Sikeston Jaycee Bootheel…

      YP
      55 Years
      in Business

      7. Comfort Inn & Suites Sikeston I-55

      Comfort Inn & Suites Sikeston I-55
      573-472-0197Call NowVisit Website
      Directions
      MotelsLodgingHotels

      109 Matthews Ln, Sikeston, MO 63801

      From Business: See why so many travelers make Comfort Inn & Suites Sikeston their hotel of choice when visiting Sikeston. Providing an ideal mix of value, comfort and convenience, it offers a…

      8. Eagle Inn Charleston

      Eagle Inn Charleston
      573-683-3900Call NowVisit Website
      Directions
      MotelsLodgingHotels

      2811 E Marshall St, Charleston, MO 63834

      OPEN 24 HOURS

      From Business: See why so many travelers make Eagle Inn their motel of choice when visiting Charleston. Providing an ideal mix of value, comfort and convenience, it offers a budget friendly…

      10. Motel 6

      Motel 6
      573-471-7400Call NowVisit Website
      Directions
      MotelsHotelsLodging

      110 S Interstate Dr, Sikeston, MO 63801

      CLOSED NOW:12:00 pm - 12:00 am

      12. Quality Inn Charleston - Sikeston

      Quality Inn Charleston - Sikeston
      573-683-4200Call NowVisit Website
      Directions
      MotelsHotels

      102 Drake St, Charleston, MO 63834

      From Business: The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get more value for your…

      We found 12 results for Motels in or near East Prairie, MO.They also appear in other related business categories including Hotels, Lodging, and Corporate Lodging. 3 of the rated businesses have 4+ star ratings.


      These businesses offer their services in one-or-more of the following languages: Dutch, French, and Greek.