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Map of East Prairie, MO

Hotels in East Prairie, MO

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5. Ramada Inn

Ramada Inn

2608 E Malone Ave, Sikeston, MO 63801

6. Best Western Plus Sikeston

Best Western Plus Sikeston

120 S Interstate Dr, Sikeston, MO 63801

OPEN 24 HOURS

"It was my first time staying at a Best Western and I enjoyed it. I was suprised to see how much space we had in our room. But, it was a good amount of space for the cost of the…"

7. Holiday Inn Express & Suites Sikeston

Holiday Inn Express & Suites Sikeston

115 Hospitality Dr, Sikeston, MO 63801

From Business: IHG Rewards Club Members: Get better savings with YOUR RATE. Book hotels direct at holidayinnexpress.com for our lowest rates. You won't find these anywhere else. Large…

YP
33 Years
in Business

8. Hampton Inn Sikeston

Hampton Inn Sikeston

1240 S Commerce Dr, Sikeston, MO 63801

OPEN 24 HOURS

From Business: Settle in for a relaxing stay at the Sikeston’s newest hotel. Our Hampton Inn Sikeston hotel is located off Highway 60 and Interstate 55, just minutes from historic downtown…

YP
6 Years
in Business

10. Days Inn

Days Inn

1330 S Main St, Sikeston, MO 63801

OPEN 24 HOURS

From Business: Days Inn is a provider of hospitality services and accommodation facility. Based in Sikeston, Mo., it offers daybreak breakfast items, such as Minute Maid juices, Kellogg's…

11. Americas Best Value Inn

Americas Best Value Inn

220 S Interstate Dr, Sikeston, MO 63801

YP
23 Years
in Business

13. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

109 Matthews Ln, Sikeston, MO 63801

From Business: See why so many travelers make Comfort Inn & Suites Sikeston their hotel of choice when visiting Sikeston. Providing an ideal mix of value, comfort and convenience, it offers a…

YP
17 Years
in Business

14. Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

102 Drake St, Charleston, MO 63834

From Business: The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get more value for your…

15. Eagle Inn Charleston

Eagle Inn Charleston

2811 E Marshall St, Charleston, MO 63834

OPEN 24 HOURS

From Business: See why so many travelers make Eagle Inn their motel of choice when visiting Charleston. Providing an ideal mix of value, comfort and convenience, it offers a budget friendly…