From Business: Best Western Plus Jackson/Cape Girardeau hotel in Jackson, Missouri! Our hotel is located just off I-55 at Exit 99. This hotel offers 80 rooms including 9 suites.Best Western…

From Business: At the Best Western Plus Jackson/Cape Girardeau you're sure to find that little something extra. With our modern amenities and thoughtful design, the Best Western Plus…

From Business: The St. Genevieve, MO Econo Lodge hotel is off Interstate 55, near all the historical, small-town highlights of Ste. Genevieve, while being a short drive from St. Louis. We…

From Business: Travel Happy® with Drury Hotels. You have enough to worry about while you're traveling. Let us take a few things off your plate, so you can focus on the good stuff. Breakfast,…

From Business: Whether traveling for business or fun, Courtyard by Marriott® makes all your travels successful by providing what you need: spacious, thoughtful guest rooms and services that…

From Business: IHG Rewards Club Members: Get better savings with YOUR RATE. Book hotels direct at candlewoodsuites.com for our lowest rates. You won't find these anywhere else. Experience…

"One of the nicest mid-range hotels I've have stayed at. Great staff, beautiful lobby and rooms. Will be back next time."

From Business: A stay at Dr. Hertich House Heritage Hotel is the perfect way to experience the history and charm of Ste. Genevieve, Missouri. Our hotel is a Heritage Hotel, built in 1850 as…

From Business: This Bavarian-style hotel off I-55 in Jackson may not look like the other Drury Inn & Suites on the outside, but our friendly staff always welcomes guests to relax in a clean,…

"The best hotel EVER!!!!!"

From Business: Comfort Suites in Jackson Missouri is an all suite property located on the edge of Cape Girardeau and Jackson Missouri. We offer an indoor pool/hot tub, fitness center, guest…

From Business: The Fairfield Inn and Suites is Cape Girardeau's newest property by Marriott that features a saltwater pool, fitness center and a free hot breakfast to fuel up your stay. Relax…

From Business: Located directly off I-55, Drury Suites Cape Girardeau is the perfect stop for business or leisure travelers. At the heart of Cape Girardeau, the hotel is just minutes away…

From Business: Whether you are visiting Missouri for business or pleasure, our Days Inn Perryville hotel has something to offer everyone. Located off I-55 near the Perry County Community Lake…

From Business: The Inn St. Gemme Beauvais is the oldest continuously operated Bed and Breakfast in Missouri. The Inn has earned a Three Star Mobil rating. It has been a recipient of the…

From Business: Willow House B&B is a historically restored Victorian home, just two blocks off the main square in Perryville, Missouri. A quite and peaceful B&B located next to willow pond…

From Business: See why so many travelers make Southern Hotel their bed and breakfast of choice when visiting Sainte Genevieve. Providing an ideal mix of value, comfort and convenience, it…

"Very quaint and quiet, low prices for the area. Well furnished including fridge and microwave. Very agreeable and wonderful service best value in the area for sure!!"

From Business: From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William…

From Business: Finding an ideal budget friendly motel in Murphysboro does not have to be difficult. Welcome to Americas Best Value Inn Murphysboro / Carbondale, a nice option for travelers…

From Business: This southern Illinois getaway is part of an extension to OUR existing lodging the Davie INN. We have been in the lodging business for 12 years NOW and are happy to ADD a cabin…