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      Hotels in Sikeston

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      1.Super 8 by Wyndham Sikeston/Miner Area

      2609 E Malone Ave, Sikeston, MO 63801

      Super 8 by Wyndham Sikeston/Miner Area

      2.Hampton Inn Sikeston

      1240 S Commerce Dr, Sikeston, MO 63801

      OPEN 24 HOURS
      Hampton Inn Sikeston

      3.Best Western Plus Sikeston

      5.0

      120 S Interstate Dr, Sikeston, MO 63801

      OPEN 24 HOURS
      Best Western Plus Sikeston

      4.Holiday Inn Express & Suites Sikeston

      115 Hospitality Dr, Sikeston, MO 63801

      Holiday Inn Express & Suites Sikeston

      5.Comfort Inn & Suites Sikeston I-55

      109 Matthews Ln, Sikeston, MO 63801

      Comfort Inn & Suites Sikeston I-55

      6.Days Inn & Suites by Wyndham Sikeston

      220 S Interstate Dr, Sikeston, MO 63801

      7.Drury Hotels Company

      2608 E Malone Ave, Sikeston, MO 63801

      8.Country Hearth Inns and Suites

      100 Matthews Ln, Sikeston, MO 63801

      Country Hearth Inns and Suites

      9.Ramada Inn

      2608 E Malone Ave, Sikeston, MO 63801

      10.TownePlace Suites Sikeston

      1239 S Commerce Dr, Sikeston, MO 63801

      11.Fairfield Inn & Suites

      1239 S Commerce Dr, Sikeston, MO 63801

      12.America's Best Value Inn & Suites

      220 S Interstate Dr, Sikeston, MO 63801

      America's Best Value Inn & Suites

      13.Thrifty Inn

      2602 E Malone Ave, Sikeston, MO 63801

      14.Motel 6

      110 S Interstate Dr, Sikeston, MO 63801

      CLOSED NOW:12:00 pm - 12:00 am
      Motel 6

      15.Grace Inn Of East Prairie

      105 N Highway Cc, East Prairie, MO 63845

      16.Eagle Inn Charleston

      2811 E Marshall St, Charleston, MO 63834

      OPEN 24 HOURS

      17.Gary & Teresa Hancock

      127 Baker Ln, East Prairie, MO 63845

      18.Quality Inn Charleston - Sikeston

      102 Drake St, Charleston, MO 63834

      Quality Inn Charleston - Sikeston

      19.Econo Lodge

      310 S Story St, Charleston, MO 63834

      Econo Lodge
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      Super 8 by Wyndham Sikeston/Miner Area

      2609 E Malone Ave, Sikeston, MO 63801

      573-471-7944

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      Hampton Inn Sikeston

      1240 S Commerce Dr, Sikeston, MO 63801

      573-621-4100

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      Best Western Plus Sikeston

      120 S Interstate Dr, Sikeston, MO 63801

      573-481-9500

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      Holiday Inn Express & Suites Sikeston

      115 Hospitality Dr, Sikeston, MO 63801

      800-345-8082

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      Comfort Inn & Suites Sikeston I-55

      109 Matthews Ln, Sikeston, MO 63801

      573-472-0197

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      Days Inn & Suites by Wyndham Sikeston

      220 S Interstate Dr, Sikeston, MO 63801

      573-564-4066

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      Drury Hotels Company

      2608 E Malone Ave, Sikeston, MO 63801

      573-472-6234

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      Country Hearth Inns and Suites

      100 Matthews Ln, Sikeston, MO 63801

      573-472-4400

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      Ramada Inn

      2608 E Malone Ave, Sikeston, MO 63801

      573-472-1885

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      TownePlace Suites Sikeston

      1239 S Commerce Dr, Sikeston, MO 63801

      573-930-0500

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      Fairfield Inn & Suites

      1239 S Commerce Dr, Sikeston, MO 63801

      573-919-7200

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      America's Best Value Inn & Suites

      220 S Interstate Dr, Sikeston, MO 63801

      573-471-9700

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      Thrifty Inn

      2602 E Malone Ave, Sikeston, MO 63801

      573-471-8660

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      Motel 6

      110 S Interstate Dr, Sikeston, MO 63801

      573-471-7400

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      Grace Inn Of East Prairie

      105 N Highway Cc, East Prairie, MO 63845

      573-649-5616

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      Eagle Inn Charleston

      2811 E Marshall St, Charleston, MO 63834

      573-683-3900

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      Gary & Teresa Hancock

      127 Baker Ln, East Prairie, MO 63845

      573-649-5616

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      Quality Inn Charleston - Sikeston

      102 Drake St, Charleston, MO 63834

      573-683-4200

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      Econo Lodge

      310 S Story St, Charleston, MO 63834

      573-683-2125

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