"One of the nicest mid-range hotels I've have stayed at. Great staff, beautiful lobby and rooms. Will be back next time."

From Business: Located directly off I-55, Drury Suites Cape Girardeau is the perfect stop for business or leisure travelers. At the heart of Cape Girardeau, the hotel is just minutes away…

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From Business: This Bavarian-style hotel off I-55 in Jackson may not look like the other Drury Inn & Suites on the outside, but our friendly staff always welcomes guests to relax in a clean,…

From Business: Travel Happy® with Drury Hotels. You have enough to worry about while you're traveling. Let us take a few things off your plate, so you can focus on the good stuff. Breakfast,…

From Business: Whether traveling for business or fun, Courtyard by Marriott® makes all your travels successful by providing what you need: spacious, thoughtful guest rooms and services that…

From Business: Comfort Suites in Jackson Missouri is an all suite property located on the edge of Cape Girardeau and Jackson Missouri. We offer an indoor pool/hot tub, fitness center, guest…

From Business: Best Western Plus Jackson/Cape Girardeau hotel in Jackson, Missouri! Our hotel is located just off I-55 at Exit 99. This hotel offers 80 rooms including 9 suites.Best Western…

From Business: The Fairfield Inn and Suites is Cape Girardeau's newest property by Marriott that features a saltwater pool, fitness center and a free hot breakfast to fuel up your stay. Relax…

From Business: From our daily free hot breakfast to our nightly cookie hour, Hampton Inn Cape Girardeau I-55 East makes you feel at home. Located on the southeast corner of I-55 and William…

From Business: The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Get more value for your…

From Business: See why so many travelers make Comfort Inn & Suites Sikeston their hotel of choice when visiting Sikeston. Providing an ideal mix of value, comfort and convenience, it offers a…

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From Business: If you’re looking for a budget friendly hotel in Charleston, look no further than Super 8 by Wyndham Charleston MO. Charleston Econo Lodge is a budget friendly hotel offering a…

From Business: Enjoy a comfortable stay at the newest hotel in Sikeston, MO. We are conveniently located off Highway 60 and Interstate 55, very close to historic downtown and a short walk to…

From Business: This wyndham Hotels affiliate is a all Suite property with large bedrooms and living rooms, 2 LED television in each room, located near restaurants, Sikeston Jaycee Bootheel…

From Business: The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. The Econo Lodge hotel in…